GREProtemics

Born in 1988, Kelly Hodge was brought into a world of novel developments in Mass Spectrometry. Much like the baby steps Kelly herself was currently making, 1989 saw the infancy of modern mass spec- the ion trap, an essential component of today’s machines, developed by Wolfgang Paul (who won the Nobel Prize in Physics for his work).

However like every young child, Paul’s idea needed time to grow, to be nurtured, so it could become the invaluable asset it is today. So we fast forward to 2002, the beginning of the golden adolescent years. Kelly, now 14, attended Lochgelly High School where she was introduced into the mind-blowing world of science, chemistry in particular caught this young teenager’s eye, a subject that very quickly became her 1st academic crush.

Mass spectrometry was also indulging in a love affair of sorts with biological macromolecules which ultimately gave birth to ESI (electrospray ionisation) and the first successful MALDI (Matrix Assisted Laser Desorption Ionization) on biological peptides. Both John Bennet Fenn and Koichi Tanaka received the Nobel Prize for Chemistry in 2002 for their respective work in the field.

Another leap in time, this one not as large and we arrive in 2006, Kelly’s academic crush had progressed into a complete love for the subject she first met at 14 and it was with this love in mind she started her undergraduate career in Biochemistry at the University of Dundee.

During this time Proteomics was just coming to the fore in the mass spectrometry world and by the time Kelly reached her final honours year and the subsequent “honour’s project”, Proteomics had also arrived in a place of invaluable importance for the mass spec community.

Kelly undertook a project in Professor Angus Lamond’s laboratory where she used mass spectrometry based proteomics to identify the spatial localization of the glucocorticoid receptors in HeLa cells.

Kelly graduated in 2010 with Bsc (Hons) in Biochemistry and five months later began working with Dr Sara ten Have, the Proteomic Consultant and Technologist in the Wellcome Trust Centre for Gene Regulation and Expression at the University of Dundee.
There she hopes to engage her fellow scientists with the wonderful joy and satisfaction mass spectrometry based proteomics can give and to facilitate the marriage of genomics and proteomics for many new users in the divison.

Miss Kelly Hodge

Proteomic Technician
Wellcome Trust Centre for Gene Regulation and Expression
College of Life Sciences
University of Dundee
Dow Street
Dundee, DD1 5EH, Scotland, UK

Phone: +44 1382 386 787
email: k.z.hodge@dundee.ac.uk